Lymphomas are a heterogeneous group of malignancies arising in the lymphoid tissue. Lymphomas are usually treated by a combination of the various therapies for eg : Chemotherapy, Radiotherapy, Bone Marrow Transplant, Stem cells procedure etc (Freedman J. ,2005). But there are lots of complications and side effects related to all the above mentioned methods (Scheinberg D. A. and Jurcic J. W., 2004).
A number of conventional therapeutic options can induce reasonably durable and sequential clinical complete responses in majority of patients (2). However, second and subsequent responses tend to be progressively shorter than those achieved earlier. In particular, most second complete responses obtained through standard chemotherapy last far less than 2 years, and the median duration is 13 months (Illidge T. and Johnson P. W. M., 2005). Follicular lymphomas (FL) are basically indolent diseases. While highly responsive to chemotherapy, the majority of lymphomas in patients remain incurable even by using various combinations of standard chemotherapy drugs. There is a need for novel therapies with less toxicity and more specific targeting of tumor cells (1).
For more on this click on link below:
A Study of Idiotypic Vaccine for Follicular Lymphoma Treatment
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