Genomic techniques used to find new diagnostic markers for testicular cancer

Numerous recent studies have demonstrated the use of genomic data, particularly gene expression signatures, as clinical prognostic and diagnostic factors in cancer. This review highlights the usage of genomic analysis to detect diagnostic markers for testicular cancer. The carcinoma in situ (CIS) cell is the common precursor of nearly all testicular germ cell tumours (TGCT). So, there is a particular need of novel markers specific to CIS and various molecular techniques are been used for the same. In particular, the focus is on recent studies showing successful usage of microarray technology, tools used for its analysis and finally a glimpse of role of Comparative Genomic Hybridisation (CGH) in discovery of new markers for CIS diagnosis.

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Genomic techniques used to find new diagnostic markers for testicular cancer